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Cellosaurus HyCyte BxPC-3 hKRAS_p.G12D_c.35G>A (CVCL_E2Q1)

[Text version]
Cell line name HyCyte BxPC-3 hKRAS_p.G12D_c.35G>A
Synonyms hKRAS_p.G12D_c.35G>A BxPC-3
Accession CVCL_E2Q1
Resource Identification Initiative To cite this cell line use: HyCyte BxPC-3 hKRAS_p.G12D_c.35G>A (RRID:CVCL_E2Q1)
Comments Population: Caucasian.
Doubling time: 48-60 hours (Hysigen=CGKO-M2185).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 6770; SMAD4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val487_Pro492delinsAla (c.1460_1474delGTGTAGGTGCTGTCA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple_edited; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous; Note=By CRISPR/Cas9 (Hysigen=CGMU-M2185).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0186 (BxPC-3)
Sex of cell Female
Age at sampling 61Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGMU-M2185
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1