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Cellosaurus NB-EbC1 (CVCL_E218)

[Text version]
Cell line name NB-EbC1
Synonyms NB-EBC1; NBEbC1; NBEBC1; EbC1; EBC1
Accession CVCL_E218
Resource Identification Initiative To cite this cell line use: NB-EbC1 (RRID:CVCL_E218)
Comments Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel.
Doubling time: 45 hours (PubMed=20922763).
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Misspelling: NB-EBcl; Note=Occasionally.
Misspelling: NB-Ebcl-1; Note=Occasionally.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
STR profile Source(s): COG; PubMed=20922763

Markers:
AmelogeninX,Y
CSF1PO12
D2S133819,20
D3S135817
D5S81810,12
D7S82012,14
D8S117911,13
D13S31711,12
D16S53912
D18S5115,20
D19S43314,15
D21S1127,32.2
FGA24,25
TH016,9.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Web pages https://www.cccells.org/PDF_Files/NB_Cell_Lines/NB-EBc1%20Cell%20Line%20Data%20Sheet.pdf
http://www.pptpinvitro.org/cell_lines_panel.php
Publications

PubMed=18724359; DOI=10.1038/nature07261
Mosse Y.P., Laudenslager M., Longo L., Cole K.A., Wood A., Attiyeh E.F., Laquaglia M.J., Sennett R., Lynch J.E., Perri P., Laureys G., Speleman F., Kim C., Hou C.-P., Hakonarson H., Torkamani A., Schork N.J., Brodeur G.M., Tonini G.P., Rappaport E., Devoto M., Maris J.M.
Identification of ALK as a major familial neuroblastoma predisposition gene.
Nature 455:930-935(2008)

PubMed=20922763; DOI=10.1002/pbc.22801
Kang M.H., Smith M.A., Morton C.L., Keshelava N., Houghton P.J., Reynolds C.P.
National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.
Pediatr. Blood Cancer 56:239-249(2011)

PubMed=28350380; DOI=10.1038/sdata.2017.33
Harenza J.L., Diamond M.A., Adams R.N., Song M.M., Davidson H.L., Hart L.S., Dent M.H., Fortina P., Reynolds C.P., Maris J.M.
Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.
Sci. Data 4:170033-170033(2017)

Cross-references
Encyclopedic resources Wikidata; Q54907506
Gene expression databases GEO; GSM2371246
GEO; GSM2394378
Polymorphism and mutation databases Cosmic; 1161996
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number14