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Cellosaurus HyCyte U251 KO-hOXSR1 (CVCL_E1N9)

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Cell line name HyCyte U251 KO-hOXSR1
Synonyms hOXSR1 knockout U251
Accession CVCL_E1N9
Resource Identification Initiative To cite this cell line use: HyCyte U251 KO-hOXSR1 (RRID:CVCL_E1N9)
Comments Population: Caucasian.
Doubling time: 48-72 hours (Hysigen=CGKO-M2266).
Knockout cell: Method=CRISPR/Cas9; HGNC; 8508; OXSR1.
Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; p.Glu242Valfs*15 (c.723_724dupTG); ClinVar=VCV000536553; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0021 (U-251MG)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2266
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1