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Cellosaurus HyCyte A-498 KO-hCBX7 (CVCL_E1IQ)

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Cell line name HyCyte A-498 KO-hCBX7
Synonyms hCBX7 knockout A-498
Accession CVCL_E1IQ
Resource Identification Initiative To cite this cell line use: HyCyte A-498 KO-hCBX7 (RRID:CVCL_E1IQ)
Comments Population: Caucasian.
Doubling time: 48-72 hours (Hysigen=CGKO-M2370).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:1557; CBX7.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:8976; PIK3CB; Simple; p.Asp1067Val (c.3200A>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:12687; VHL; Simple; p.Gly144Serfs*14 (c.426_429delTGAC); Zygosity=Homozygous (from parent cell line).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1056 (A-498)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2370
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2