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Cellosaurus SCp2 (CVCL_E1I2)

[Text version]
Cell line name SCp2
Synonyms scp2; SubClone petit 2
Accession CVCL_E1I2
Resource Identification Initiative To cite this cell line use: SCp2 (RRID:CVCL_E1I2)
Comments Characteristics: When given lactogenic hormones and basement membrane ECM in serum-free medium, they arrest growth, form three-dimensional alveolar structures, and express beta-casein (CelloPub=CLPUB00773).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_E1I1 (CID 9)
Children:
CVCL_E1I4 (SCp2-antisense Id-1)CVCL_E1I3 (SCp2-Id-1)
Sex of cell Female
Age at sampling 1Y
Category Spontaneously immortalized cell line
STR profile Source(s): Millipore=SCC458

Markers:
Mouse STR 1-113,14
Mouse STR 1-217
Mouse STR 2-116
Mouse STR 3-214
Mouse STR 4-221.3
Mouse STR 5-514
Mouse STR 6-419
Mouse STR 6-712
Mouse STR 7-126.2
Mouse STR 8-113
Mouse STR 11-218
Mouse STR 12-116
Mouse STR 13-116.2
Mouse STR 15-322.3
Mouse STR 17-216,17
Mouse STR 18-317,18
Mouse STR 19-213
Mouse STR X-124

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Publications

CLPUB00773
Desprez P.-Y., Roskelley C.D., Campisi J., Bissell M.J.
Isolation of functional cell lines from a mouse mammary epithelial cell strain: the importance of basement membrane and cell-cell interaction.
Mol. Cell. Differ. 1:99-110(1993)

PubMed=7528920; DOI=10.1073/pnas.91.26.12378; PMCID=PMC45441
Roskelley C.D., Desprez P.-Y., Bissell M.J.
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction.
Proc. Natl. Acad. Sci. U.S.A. 91:12378-12382(1994)

PubMed=7760836; DOI=10.1128/MCB.15.6.3398; PMCID=PMC230574
Desprez P.-Y., Hara E., Bissell M.J., Campisi J.
Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1.
Mol. Cell. Biol. 15:3398-3404(1995)

PubMed=9671467; DOI=10.1128/MCB.18.8.4577; PMCID=PMC109043
Desprez P.-Y., Lin C.Q., Thomasset N., Sympson C.J., Bissell M.J., Campisi J.
A novel pathway for mammary epithelial cell invasion induced by the helix-loop-helix protein Id-1.
Mol. Cell. Biol. 18:4577-4588(1998)

Cross-references
Cell line collections (Providers) Millipore; SCC458
Entry history
Entry creation10-Sep-2024
Last entry update10-Apr-2025
Version number2