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Cellosaurus HeLa M FAM117A1/VPS13B-DKO (CVCL_E1HT)

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Cell line name HeLa M FAM117A1/VPS13B-DKO
Synonyms HeLa M VPS13B-KO 1 FAM177A1-KO; VPS13BKO1,FAM177A1 DKO HeLaM
Accession CVCL_E1HT
Resource Identification Initiative To cite this cell line use: HeLa M FAM117A1/VPS13B-DKO (RRID:CVCL_E1HT)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; 19829; FAM177A1.
Knockout cell: Method=CRISPR/Cas9; HGNC; 2183; VPS13B.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E1HQ (HeLa M VPS13B-KO 1)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=38187698; DOI=10.1101/2023.12.18.572081; PMCID=PMC10769246
Ugur B., Schueder F., Shin J., Hanna M.G. 4th, Wu Y.-M., Leonzino M., Su M.-H., McAdow A.R., Wilson C., Postlethwait J.H., Solnica-Krezel L., Bewersdorf J., De Camilli P.
VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1.
bioRxiv 2023:12.18.572081-12.18.572081(2023)

Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1