Cellosaurus N2a[TRb1]-274A+B Clone AB2 (CVCL_E1GU)
| Cell line name | N2a[TRb1]-274A+B Clone AB2 |
|---|---|
| Synonyms | N2a[TRb1]-274 A+B Clone AB-2 |
| Accession | CVCL_E1GU |
| Resource Identification Initiative | To cite this cell line use: N2a[TRb1]-274A+B Clone AB2 (RRID:CVCL_E1GU) |
| Comments | Characteristics: Using CRISPR/Cas9 mutations were introduced in the thyroid hormone response element (TRE) of the Dnmt3a gene (PubMed=27387481). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11799; THRB. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Derived from site: In situ; Peripheral nervous system; UBERON=UBERON_0000010. Cell type: Neural crest derived neuroblast; CL=CL_0002676. |
| Disease | Mouse neuroblastoma (NCIt: C21993) |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: A/J. |
| Hierarchy | Parent: CVCL_E1GT (Neuro2A[TRb1]) |
| Sex of cell | Male |
| Category | Cancer cell line |
| Publications | PubMed=27387481; DOI=10.1210/en.2015-1529; PMCID=PMC5007891 |
| Cross-references | |
| Cell line collections (Providers) | Kerafast; EMU060 |
| Entry history | |
| Entry creation | 10-Sep-2024 |
| Last entry update | 19-Dec-2024 |
| Version number | 2 |