ID   MDBK CD46 KO
AC   CVCL_E1FE
SY   CD46(-)MDBK
RX   PubMed=32781607;
CC   Virology: Much less susceptible than parent cell line to infection by bovine viral diarrhea virus (BVDV) (PubMed=32781607).
CC   Knockout cell: Method=siRNA knockdown; VGNC; -; CD46.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9913; ! Bos taurus (Bovine)
HI   CVCL_0421 ! MDBK
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 10-09-24; Last updated: 10-09-24; Version: 1
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RX   PubMed=32781607; DOI=10.3390/v12080859; PMCID=PMC7472008;
RA   Szillat K.P., Koethe S., Wernike K., Hoper D., Beer M.;
RT   "A CRISPR/Cas9 generated bovine CD46-knockout cell line -- a tool to
RT   elucidate the adaptability of bovine viral diarrhea viruses (BVDV).";
RL   Viruses 12:859.1-859.13(2020).
//