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Cellosaurus Ubigene U-251 MG SLC7A11 KO (CVCL_E1E5)

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Cell line name Ubigene U-251 MG SLC7A11 KO
Synonyms SLC7A11 Knockout cell line (U-251 MG)
Accession CVCL_E1E5
Resource Identification Initiative To cite this cell line use: Ubigene U-251 MG SLC7A11 KO (RRID:CVCL_E1E5)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11059; SLC7A11.
Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu242Valfs*15 (c.723_724dupTG); ClinVar=VCV000536553; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0021 (U-251MG)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-H925
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2