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Cellosaurus Ubigene SK-OV-3 RIPK1 KO (CVCL_E1CB)

[Text version]
Cell line name Ubigene SK-OV-3 RIPK1 KO
Synonyms RIPK1 Knockout cell line (SK-OV-3)
Accession CVCL_E1CB
Resource Identification Initiative To cite this cell line use: Ubigene SK-OV-3 RIPK1 KO (RRID:CVCL_E1CB)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 10019; RIPK1.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-HJ062
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1