Cellosaurus cell line Ubigene PANC-1 PTEN KO (CVCL

Cross-references
Cell line name	Ubigene PANC-1 PTEN KO
Synonyms	PTEN Knockout cell line (PANC-1)
Accession	CVCL_E1AK
Resource Identification Initiative	To cite this cell line use: Ubigene PANC-1 PTEN KO (RRID:CVCL_E1AK)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; 9588; PTEN. Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0480 (PANC-1)
Sex of cell	Male
Age at sampling	56Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YKO-HJ117
Entry history
Entry creation	10-Sep-2024
Last entry update	10-Sep-2024
Version number	1