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Cellosaurus Ubigene OVCAR-3 CDR1 KO (CVCL_E1AC)

[Text version]
Cell line name Ubigene OVCAR-3 CDR1 KO
Synonyms CDR1 Knockout cell line (OVCAR-3)
Accession CVCL_E1AC
Resource Identification Initiative To cite this cell line use: Ubigene OVCAR-3 CDR1 KO (RRID:CVCL_E1AC)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:1798; CDR1.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; c.1746-2A>T; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0465 (OVCAR-3)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-H123
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2