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Cellosaurus PrEC LHSR (CVCL_E123)

[Text version]
Cell line name PrEC LHSR
Synonyms LHSR
Accession CVCL_E123
Resource Identification Initiative To cite this cell line use: PrEC LHSR (RRID:CVCL_E123)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E3G2 (PrEC LHSR-AR)
Originate from same individual CVCL_V626 ! PrEC LH
CVCL_9U68 ! PrEC LHMK
CVCL_9U69 ! PrEC LHS
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=15604246; DOI=10.1158/0008-5472.CAN-04-2938
Berger R., Febbo P.G., Majumder P.K., Zhao J.J., Mukherjee S., Signoretti S., Campbell K.T., Sellers W.R., Roberts T.M., Loda M., Golub T.R., Hahn W.C.
Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells.
Cancer Res. 64:8867-8875(2004)

PubMed=21747944; DOI=10.1371/journal.pone.0021650; PMCID=PMC3128608
Leshem O., Madar S., Kogan-Sakin I., Kamer I., Goldstein I., Brosh R., Cohen Y., Jacob-Hirsch J., Ehrlich M., Ben-Sasson S., Goldfinger N., Loewenthal R., Gazit E., Rotter V., Berger R.
TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model.
PLoS ONE 6:E21650-E21650(2011)

Cross-references
Encyclopedic resources Wikidata; Q54948346
Experimental variables resources EFO; EFO_0002797
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number11