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Cellosaurus Ubigene NCI-H1975 BAD KO (CVCL_E0ZS)

[Text version]
Cell line name Ubigene NCI-H1975 BAD KO
Synonyms BAD Knockout cell line (NCI-H1975)
Accession CVCL_E0ZS
Resource Identification Initiative To cite this cell line use: Ubigene NCI-H1975 BAD KO (RRID:CVCL_E0ZS)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 936; BAD.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 3236; EGFR; Simple; p.Leu858Arg (c.2573T>G); ClinVar=VCV000016609; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly118Asp (c.353G>A); ClinVar=VCV000156446; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1511 (NCI-H1975)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-H1099
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1