Cellosaurus cell line Ubigene NB4 TLN1 KO (CVCL

Cross-references
Cell line name	Ubigene NB4 TLN1 KO
Synonyms	TLN1 Knockout cell line (NB4)
Accession	CVCL_E0ZE
Resource Identification Initiative	To cite this cell line use: Ubigene NB4 TLN1 KO (RRID:CVCL_E0ZE)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; 11845; TLN1. Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Gene fusion; HGNC; 9113; PML + HGNC; 9864; RARA; Name(s)=PML-RARA (from parent cell line). Mutation; HGNC; 6407; KRAS; Simple; p.Ala18Asp (c.53C>A); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease	Acute promyelocytic leukemia with PML-RARA (NCIt: C3182) Acute promyelocytic leukemia (ORDO: Orphanet_520)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0005 (NB4)
Sex of cell	Female
Age at sampling	23Y
Category	Cancer cell line
Cell line collections (Providers)	Ubigene; YKO-H400
Entry history
Entry creation	10-Sep-2024
Last entry update	10-Sep-2024
Version number	1