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Cellosaurus Ubigene Hep G2 PPP1R12B KO (CVCL_E0UT)

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Cell line name Ubigene Hep G2 PPP1R12B KO
Synonyms PPP1R12B Knockout cell line (Hep G2)
Accession CVCL_E0UT
Resource Identification Initiative To cite this cell line use: Ubigene Hep G2 PPP1R12B KO (RRID:CVCL_E0UT)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 7619; PPP1R12B.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-H427
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1