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Cellosaurus WA26 (CVCL_E081)

[Text version]
Cell line name WA26
Synonyms WAe026-A
Accession CVCL_E081
Resource Identification Initiative To cite this cell line use: WA26 (RRID:CVCL_E081)
Comments Group: Clinical grade pluripotent cell line.
From: University of Wisconsin; Madison; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-12-0197.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Unspecified; Note=Somatic mutation acquired during proliferation (PubMed=28445466).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): WiCell=wa26

Markers:
AmelogeninX
CSF1PO11
D5S81812
D7S82010
D13S31711,12
D16S53912,14
TH017,10
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Web pages https://www.wicell.org/media/Ads/2013.ISSCR.DerivationFinal.pdf
Publications

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line collections (Providers) WiCell; wa26
Cell line databases/resources hPSCreg; WAe026-A
NIHhESC; NIHhESC-12-0197
Encyclopedic resources Wikidata; Q54993533
Entry history
Entry creation22-Oct-2012
Last entry update10-Sep-2024
Version number22