Cellosaurus HAP1 RPS6KA4 (-) RPS6KA5 (-) 1 (CVCL_DX53)
| Cell line name | HAP1 RPS6KA4 (-) RPS6KA5 (-) 1 |
|---|---|
| Synonyms | HZGHC006960c001; Double knockout cell line RPS6KA4 1bp insertion in exon 4 and RPS6KA5 19bp deletion in exon 3 |
| Accession | CVCL_DX53 |
| Resource Identification Initiative | To cite this cell line use: HAP1 RPS6KA4 (-) RPS6KA5 (-) 1 (RRID:CVCL_DX53) |
| Comments | Group: Haploid karyotype cell line. Knockout cell: Method=CRISPR/Cas9; HGNC; 10433; RPS6KA4. Knockout cell: Method=CRISPR/Cas9; HGNC; 10434; RPS6KA5. Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371. |
| Sequence variations |
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| Disease | Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174) Chronic myeloid leukemia (ORDO: Orphanet_521) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_TJ66 (HAP1 RPS6KA5 (-) 1) |
| Sex of cell | Male |
| Age at sampling | 40Y |
| Category | Cancer cell line |
| Cross-references | |
| Cell line collections (Providers) | Horizon_Discovery; HZGHC006960c001 |
| Entry history | |
| Entry creation | 30-Jan-2024 |
| Last entry update | 30-Jan-2024 |
| Version number | 1 |