| Cell line name |
Jurkat J77 cl20 |
|---|
| Synonyms |
Jurkat J77cl20; J77 clone 20; J77cl20; J77.20 |
|---|
| Accession |
CVCL_DS02 |
|---|
| Resource Identification Initiative |
To cite this cell line use: Jurkat J77 cl20 (RRID:CVCL_DS02) |
|---|
| Comments |
Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084. |
|---|
| Sequence variations |
- Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11491; SYK; Simple; p.Met34Hisfs*3 (c.98_99insG); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
|
|---|
| Disease |
Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_DS01 (Jurkat J77) |
|---|
| Sex of cell |
Male |
|---|
| Age at sampling |
14Y |
|---|
| Category |
Cancer cell line |
|---|
| Publications | PubMed=7759540; DOI=10.1074/jbc.270.21.12839
Niedergang F., Hemar A., Hewitt C.R.A., Owen M.J., Dautry-Varsat A., Alcover A.
The Staphylococcus aureus enterotoxin B superantigen induces specific T cell receptor down-regulation by increasing its internalization.
J. Biol. Chem. 270:12839-12845(1995) |
|---|
| Cross-references |
|---|
| Cell line databases/resources |
cancercelllines; CVCL_DS02
|
|---|
| Encyclopedic resources |
Wikidata; Q54899135
|
|---|
| Proteomic databases |
PRIDE; PXD001549
|
|---|
| Entry history |
|---|
| Entry creation | 13-Jul-2016 |
|---|
| Last entry update | 05-Oct-2023 |
|---|
| Version number | 16 |
|---|
