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Cellosaurus MH/Nike (CVCL_DN29)

[Text version]
Cell line name MH/Nike
Synonyms Nike; Nike/MH; Nike / MH
Accession CVCL_DN29
Resource Identification Initiative To cite this cell line use: MH/Nike (RRID:CVCL_DN29)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 25 hours (PubMed=27257868).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; VGNC; VGNC:43761; NF1; Simple; p.Ala2176fs (c.6525delG); Zygosity=Homozygous (PubMed=31175136).
Disease Canine histiocytic sarcoma (NCIt: C128125)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=27197945; PubMed=31175136

Markers:
Dog FHC2010235
Dog FHC2054164
Dog FHC2079275,291
Dog PEZ1115
Dog PEZ12270,274
Dog PEZ20176
Dog PEZ3119,139
Dog PEZ5107,115
Dog PEZ6167,187
Dog PEZ8240

Run an STR similarity search on this cell line
Publications

PubMed=27257868; DOI=10.1371/journal.pone.0156689; PMCID=PMC4892608
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=26842912; DOI=10.1111/vco.12197
Hartley G., Faulhaber E.A., Caldwell A., Coy J., Kurihara J.N., Guth A., Regan D.P., Dow S.W.
Immune regulation of canine tumour and macrophage PD-L1 expression.
Vet. Comp. Oncol. 15:534-549(2017)

PubMed=27197945; DOI=10.1111/vco.12192; PMCID=PMC5656225
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346; PMCID=PMC6679748
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole-exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

Cross-references
Encyclopedic resources Wikidata; Q54905518
Gene expression databases GEO; GSM1974795
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number9