| Cell line name |
MH/Nike |
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| Synonyms |
Nike; Nike/MH; Nike / MH |
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| Accession |
CVCL_DN29 |
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| Resource Identification Initiative |
To cite this cell line use: MH/Nike (RRID:CVCL_DN29) |
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| Comments |
Part of: FACC canine tumor cell line panel.
Doubling time: 25 hours (PubMed=27257868).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray. |
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| Sequence variations |
- Mutation; VGNC; VGNC:43761; NF1; Simple; p.Ala2176fs (c.6525delG); Zygosity=Homozygous (PubMed=31175136).
|
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| Disease |
Canine histiocytic sarcoma (NCIt: C128125) |
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| Species of origin |
Canis lupus familiaris (Dog) (Canis familiaris)
(NCBI Taxonomy: 9615) |
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| Sex of cell |
Sex unspecified |
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| Age at sampling |
Age unspecified |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): PubMed=27197945; PubMed=31175136
Markers:| Dog FHC2010 | 235 |
| Dog FHC2054 | 164 |
| Dog FHC2079 | 275,291 |
| Dog PEZ1 | 115 |
| Dog PEZ12 | 270,274 |
| Dog PEZ20 | 176 |
| Dog PEZ3 | 119,139 |
| Dog PEZ5 | 107,115 |
| Dog PEZ6 | 167,187 |
| Dog PEZ8 | 240 |
Run an STR similarity search on this cell line |
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| Publications | PubMed=27257868; DOI=10.1371/journal.pone.0156689; PMCID=PMC4892608
Junko Maeda, Coral Eva Froning, Colleen A. Brents, Barbara J. Rose, Douglas H. Thamm, Takamitsu A. Kato;
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:e0156689.1-e0156689.18(2016) PubMed=26842912; DOI=10.1111/vco.12197
Genevieve Hartley, Erica Ann Faulhaber, Alison Caldwell, Jonathan Coy, Jade N. Kurihara, Amanda Guth, Daniel P. Regan, Steven W. Dow;
Immune regulation of canine tumour and macrophage PD-L1 expression.
Vet. Comp. Oncol. 15:534-549(2017) PubMed=27197945; DOI=10.1111/vco.12192; PMCID=PMC5656225
Jared S. Fowles, Deanna D. Dailey, Daniel L. Gustafson, Douglas H. Thamm, Dawn L. Duval;
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017) PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346; PMCID=PMC6679748
Sunetra Das, Rupa Idate, Kathryn E. Cronise, Daniel L. Gustafson, Dawn L. Duval;
Identifying candidate druggable targets in canine cancer cell lines using whole-exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54905518
|
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| Gene expression databases |
GEO; GSM1974795
|
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| Entry history |
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| Entry creation | 13-Jul-2016 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 10 |
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