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Cellosaurus Hep3BLAP-II (CVCL_DI40)

[Text version]
Cell line name Hep3BLAP-II
Accession CVCL_DI40
Resource Identification Initiative To cite this cell line use: Hep3BLAP-II (RRID:CVCL_DI40)
Comments Population: African American.
Karyotypic information: Has lost chromosome Y.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1834; CEBPB (Note=Isoform LAP).
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:903; AXIN1; Simple; p.Arg146Ter (c.436C>T); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Ser576Ter (c.1727C>G); Zygosity=Homozygous (from parent cell line).
Disease Childhood hepatocellular carcinoma (NCIt: C7955)
Pediatric hepatocellular carcinoma (ORDO: Orphanet_33402)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0326 (Hep 3B2.1-7)
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
Publications

PubMed=21145827; DOI=10.1016/j.jhep.2010.09.021
Saint-Auret G., Danan J.-L., Hiron M., Blache C., Sulpice E., Tendil S., Daveau M., Gidrol X., Salier J.-P.
Characterization of the transcriptional signature of C/EBPbeta isoforms (LAP/LIP) in Hep3B cells: implication of LIP in pro-survival functions.
J. Hepatol. 54:1185-1194(2011)

Cross-references
Encyclopedic resources Wikidata; Q54882808
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number13