Cellosaurus cell line HBEC2-E (CVCL

Cellosaurus HBEC2-E (CVCL_DH91)

Cross-references
Cell line name	HBEC2-E
Synonyms	HBEC2 HPV16 E6/E7
Accession	CVCL_DH91
Resource Identification Initiative	To cite this cell line use: HBEC2-E (RRID:CVCL_DH91)
Comments	Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Omics: Transcriptomics; Microarray. Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031. Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_X490 ! HBEC2-KT
Sex of cell	Male
Age at sampling	68Y
Category	Transformed cell line
Publications	PubMed=15604268; DOI=10.1158/0008-5472.CAN-04-3703 Ruben D. Ramirez, Shelley Sheridan, Luc Girard, Mitsuo Sato, Young Kim, Jon Pollack, Michael Peyton, Ying Zou, Jonathan M. Kurie, J. Michael DiMaio, Sara Milchgrub ...Show all 21 authors... , Alice L. Smith, Rhonda F. Souza, Laura Gilbey, Xi Zhang, Kenia G. Gandia, Melville B. Vaughan, Woodring Erik Wright, Adi F. Gazdar, Jerry W. Shay, John D. Minna; Show fewer authors Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res. 64:9027-9034(2004)
Encyclopedic resources	Wikidata; Q54881393
Gene expression databases	GEO; GSM171892 GEO; GSM253435
Entry history
Entry creation	13-Jul-2016
Last entry update	14-Aug-2025
Version number	14