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Cellosaurus MGH131-2 (CVCL_DH53)

[Text version]
Cell line name MGH131-2
Accession CVCL_DH53
Resource Identification Initiative To cite this cell line use: MGH131-2 (RRID:CVCL_DH53)
Comments Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:3236; EGFR; Unexplicit; Ex19del; Zygosity=Unspecified (PubMed=25758528).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_DH52 ! MGH131-1
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=25758528; DOI=10.1038/ncomms7377; PMCID=PMC4357281
Niederst M.J., Sequist L.V., Poirier J.T., Mermel C.H., Lockerman E.L., Garcia A.R., Katayama R., Costa C., Ross K.N., Moran T., Howe E., Fulton L.E., Mulvey H.E., Bernardo L.A., Mohamoud F., Miyoshi N., VanderLaan P.A., Costa D.B., Janne P.A., Borger D.R., Ramaswamy S., Shioda T., Iafrate A.J., Getz G., Rudin C.M., Mino-Kenudson M., Engelman J.A.
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer.
Nat. Commun. 6:6377.1-6377.10(2015)

Cross-references
Encyclopedic resources Wikidata; Q54905477
Gene expression databases GEO; GSM1568554
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number9