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Cellosaurus SVpgC2a (CVCL_DG34)

[Text version]
Cell line name SVpgC2a
Accession CVCL_DG34
Resource Identification Initiative To cite this cell line use: SVpgC2a (RRID:CVCL_DG34)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Oral cavity, buccal mucosa; UBERON=UBERON_0006956.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_DH25 (SVpgC2a-FOXM1B)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=7586160; DOI=10.1093/carcin/16.10.2515
Kulkarni P.S., Sundqvist K., Betsholtz C., Hoglund P., Wiman K.G., Zhivotovsky B., Bertolero F., Liu Y., Grafstrom R.C.
Characterization of human buccal epithelial cells transfected with the simian virus 40 T-antigen gene.
Carcinogenesis 16:2515-2521(1995)

PubMed=11377230; DOI=10.1016/S1368-8375(00)00089-0
Hansson A., Bloor B.K., Haig Y., Morgan P.R., Ekstrand J., Grafstrom R.C.
Expression of keratins in normal, immortalized and malignant oral epithelia in organotypic culture.
Oral Oncol. 37:419-430(2001)

PubMed=15651925; DOI=10.1177/026119290403200412
Staab C.A., Vondracek M., Custodio H., Johansson K., Nilsson J.A., Morgan P., Hoog J.-O., Cotgreave I.A., Grafstrom R.C.
Modelling of normal and premalignant oral tissue by using the immortalised cell line, SVpgC2a: a review of the value of the model.
Altern. Lab. Anim. 32:401-405(2004)

PubMed=18186669; DOI=10.1177/026119290703500603
Ceder R., Merne M., Staab C.A., Nilsson J.A., Hoog J.-O., Dressler D., Engelhart K., Grafstrom R.C.
The application of normal, SV40 T-antigen-immortalised and tumour-derived oral keratinocytes, under serum-free conditions, to the study of the probability of cancer progression as a result of environmental exposure to chemicals.
Altern. Lab. Anim. 35:621-639(2007)

PubMed=19287496; DOI=10.1371/journal.pone.0004849
Gemenetzidis E., Bose A., Riaz A.M., Chaplin T., Young B.D., Ali M., Sugden D., Thurlow J.K., Cheong S.-C., Teo S.-H., Wan H., Waseem A., Parkinson E.K., Fortune F., Teh M.-T.
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation.
PLoS ONE 4:E4849-E4849(2009)

CLPUB00346
Ceder R.
Cancer biomarker discovery by in vitro systems biology.
Thesis PhD (2011), Karolinska Institutet, Sweden

Cross-references
Encyclopedic resources Wikidata; Q54971035
Gene expression databases GEO; GSM298193
GEO; GSM190619
GEO; GSM190620
GEO; GSM966935
GEO; GSM966936
GEO; GSM966937
Entry history
Entry creation13-Jul-2016
Last entry update29-Jun-2023
Version number6