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Cellosaurus UW473 (CVCL_DG14)

[Text version]
Cell line name UW473
Synonyms Uw-473; UW 473
Accession CVCL_DG14
Resource Identification Initiative To cite this cell line use: UW473 (RRID:CVCL_DG14)
Comments Doubling time: 25 +- 0.7 hours (PubMed=31346954).
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Medulloblastoma, SHH-activated, TP53-mutant (NCIt: C129442)
Medulloblastoma (ORDO: Orphanet_616)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=15814657; DOI=10.1158/1078-0432.CCR-04-2045
Bobola M.S., Silber J.R., Ellenbogen R.G., Geyer J.R., Blank A., Goff R.D.
O6-methylguanine-DNA methyltransferase, O6-benzylguanine, and resistance to clinical alkylators in pediatric primary brain tumor cell lines.
Clin. Cancer Res. 11:2747-2755(2005)

PubMed=20847082; DOI=10.1093/neuonc/noq091; PMCID=PMC3018940
Teider N., Scott D.K., Neiss A., Weeraratne S.D., Amani V.M., Wang Y.-F., Marquez V.E., Cho Y.-J., Pomeroy S.L.
Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma.
Neuro-oncol. 12:1244-1256(2010)

PubMed=22723427; DOI=10.1093/neuonc/nos130; PMCID=PMC3424207
Sikkema A.H., den Dunnen W.F.A., Hulleman E., van Vuurden D.G., Garcia-Manero G., Yang H., Scherpen F.J.G., Kampen K.R., Hoving E.W., Kamps W.A., Diks S.H., Peppelenbosch M.P., de Bont E.S.J.M.
EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion.
Neuro-oncol. 14:1125-1135(2012)

PubMed=23325114; DOI=10.1007/s10616-012-9529-z; PMCID=PMC3967617
Castro-Gamero A.M., Borges K.S., Lira R.C., Andrade A.F., Fedatto P.F., Cruzeiro G.A.V., Bonfim Silva R., Fontes A.M., Valera E.T., Bobola M.S., Scrideli C.A., Tone L.G.
Chromosomal heterogeneity and instability characterize pediatric medulloblastoma cell lines and affect neoplastic phenotype.
Cytotechnology 65:871-885(2013)

PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028
Ivanov D.P., Coyle B., Walker D.A., Grabowska A.M.
In vitro models of medulloblastoma: choosing the right tool for the job.
J. Biotechnol. 236:10-25(2016)

PubMed=27812533; DOI=10.1016/j.dib.2016.10.004; PMCID=PMC5079239
Ivanov D.P., Walker D.A., Coyle B., Grabowska A.M.
Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines.
Data Brief 9:696-698(2016)

PubMed=31346954; DOI=10.1007/s10616-019-00332-3; PMCID=PMC6787134
Bonfim Silva R., Salomao K.B., de Andrade Pimentel T.V.C., de Oliveira Menezes C.C.B., Palma P.V.B., Fontes A.M.
Biological characterization of the UW402, UW473, ONS-76 and DAOY pediatric medulloblastoma cell lines.
Cytotechnology 71:893-903(2019)

Cross-references
Encyclopedic resources Wikidata; Q54992384
Entry history
Entry creation13-Jul-2016
Last entry update29-Jun-2023
Version number9