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Cellosaurus HH-B2 (CVCL_DF85)

[Text version]
Cell line name HH-B2
Synonyms HHB2
Accession CVCL_DF85
Resource Identification Initiative To cite this cell line use: HH-B2 (RRID:CVCL_DF85)
Comments Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
Omics: Variations; Array-based CGH.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Disease Primary effusion lymphoma (NCIt: C6915)
Primary effusion lymphoma (ORDO: Orphanet_48686)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=10846108; DOI=10.1128/JVI.74.13.6207-6212.2000; PMCID=PMC112123
Gradoville L., Gerlach J., Grogan E., Shedd D., Nikiforow S., Metroka C., Miller G.
Kaposi's sarcoma-associated herpesvirus open reading frame 50/Rta protein activates the entire viral lytic cycle in the HH-B2 primary effusion lymphoma cell line.
J. Virol. 74:6207-6212(2000)

PubMed=21685375; DOI=10.1182/blood-2010-12-323659; PMCID=PMC3158728
Roy D., Sin S.-H., Damania B., Dittmer D.P.
Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines.
Blood 118:e32-e39(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_DF85
Encyclopedic resources Wikidata; Q54887342
Gene expression databases GEO; GSM634738
Polymorphism and mutation databases Progenetix; CVCL_DF85
Entry history
Entry creation13-Jul-2016
Last entry update10-Apr-2025
Version number11