ID   L56Br-C1
AC   CVCL_DF84
SY   L56-BR-C1; L56BrC1
DR   BTO; BTO_0004832
DR   cancercelllines; CVCL_DF84
DR   GEO; GSM155216
DR   Progenetix; CVCL_DF84
DR   Wikidata; Q54901048
RX   PubMed=11846806;
RX   PubMed=12649339;
RX   PubMed=17334996;
CC   Characteristics: Established from the xenograft L56Br-X1 (PubMed=12649339).
CC   Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Gln563Ter (c.1687C>T) (1806C>T); ClinVar=VCV000037426; Zygosity=Hemizygous (PubMed=12649339).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser215Ile (c.644G>T); ClinVar=VCV000376660; Zygosity=Unspecified (PubMed=12649339).
CC   Omics: Array-based CGH.
CC   Derived from site: Metastatic; Axillary lymph node; UBERON=UBERON_0001097.
DI   NCIt; C36100; BRCA1-associated hereditary breast and ovarian cancer syndrome
DI   NCIt; C4872; Breast carcinoma
DI   ORDO; Orphanet_145; Hereditary breast and ovarian cancer syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 19-12-24; Version: 11
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RX   PubMed=11846806; DOI=10.1046/j.0014-2956.2001.02744.x;
RA   Hegardt C., Johannsson O.T., Oredsson S.M.;
RT   "Rapid caspase-dependent cell death in cultured human breast cancer
RT   cells induced by the polyamine analogue
RT   N(1),N(11)-diethylnorspermine.";
RL   Eur. J. Biochem. 269:1033-1039(2002).
//
RX   PubMed=12649339; DOI=10.1097/01.LAB.0000060030.10652.8C;
RA   Johannsson O.T., Staff S., Vallon-Christersson J., Kytola S.,
RA   Gudjonsson T., Rennstam K., Hedenfalk I.A., Adeyinka A., Kjellen E.,
RA   Wennerberg J., Baldetorp B., Petersen O.W., Olsson H., Oredsson S.M.,
RA   Isola J.J., Borg A.;
RT   "Characterization of a novel breast carcinoma xenograft and cell line
RT   derived from a BRCA1 germ-line mutation carrier.";
RL   Lab. Invest. 83:387-396(2003).
//
RX   PubMed=17334996; DOI=10.1002/gcc.20438;
RA   Jonsson G., Staaf J., Olsson E., Heidenblad M.,
RA   Vallon-Christersson J., Osoegawa K., de Jong P.J., Oredsson S.M.,
RA   Ringner M., Hoglund M., Borg A.;
RT   "High-resolution genomic profiles of breast cancer cell lines assessed
RT   by tiling BAC array comparative genomic hybridization.";
RL   Genes Chromosomes Cancer 46:543-558(2007).
//