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Cellosaurus NGC0211 (CVCL_DF65)

[Text version]
Cell line name NGC0211
Accession CVCL_DF65
Resource Identification Initiative To cite this cell line use: NGC0211 (RRID:CVCL_DF65)
Comments Biotechnology: Used in NsG0202.1, an encapsulated cell biodelivery device capable of local delivery of NGF to the brain so at to treat the cognitive decline in Alzheimer disease patients.
Characteristics: Contains 4 integrated copies of the NGF gene.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7808; NGF.
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0145 (ARPE-19)
Sex of cell Male
Age at sampling 19Y
Category Spontaneously immortalized cell line
Publications

DOI=10.2174/1875043501205010035
Fjord-Larsen L., Kusk P., Torp M., Sorensen J.C.H., Ettrup K., Bjarkam C.R., Tornoe J., Juliusson B., Wahlberg L.U.
Encapsulated cell biodelivery of transposon-mediated high-dose NGF to the Gottingen mini pig basal forebrain.
Open Tissue Eng. Regen. Med. J. 5:35-42(2012)

PubMed=22113314; DOI=10.1038/gt.2011.178
Fjord-Larsen L., Kusk P., Emerich D.F., Thanos C.G., Torp M., Bintz B., Tornoe J., Johnsen A.H., Wahlberg L.U.
Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer.
Gene Ther. 19:1010-1017(2012)

Cross-references
Encyclopedic resources Wikidata; Q54930466
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number11