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Cellosaurus T101 [Mouse hybridoma against human CD5] (CVCL_DC79)

[Text version]
Cell line name T101 [Mouse hybridoma against human CD5]
Accession CVCL_DC79
Resource Identification Initiative To cite this cell line use: T101 [Mouse hybridoma against human CD5] (RRID:CVCL_DC79)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8023.
Monoclonal antibody isotype: IgG2a.
Monoclonal antibody target: UniProtKB; P06127; Human CD5.
Anecdotal: The T101 mAb was one of the earliest mAbs to be tested in clinical trials against cutaneous T cell lymphoma (CTCL) and chronic lymphocytic leukemia (CLL).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

CLPUB00335
Royston I., Majda J.A., Baird S.M., Meserve B.L., Griffiths J.C.
Monoclonal antibody specific for human T lymphocytes: identification of normal and malignant T-cells.
Blood 54 Suppl. 1:106a-106a(1979)

PubMed=6993560; DOI=10.4049/jimmunol.125.2.725
Royston I., Majda J.A., Baird S.M., Meserve B.L., Griffiths J.C.
Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin.
J. Immunol. 125:725-731(1980)

Patent=US4675386
Royston I., Majda J.A., Yamamoto G.
Monoclonal antibody methods and compositions specific for single antigens in antigen aggregates.
Patent number US4675386, 23-Jun-1987

Cross-references
Encyclopedic resources Wikidata; Q54971407
Entry history
Entry creation13-Jul-2016
Last entry update21-Mar-2023
Version number6