Cellosaurus H4L1.1c4 (CVCL_DC27)
Cell line name | H4L1.1c4 |
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Synonyms | H4IIE.Luc |
Accession | CVCL_DC27 |
Resource Identification Initiative | To cite this cell line use: H4L1.1c4 (RRID:CVCL_DC27) |
Comments | Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists. Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
Disease | Rat hepatocellular carcinoma (NCIt: C60416) |
Species of origin | Rattus norvegicus (Rat)
(NCBI Taxonomy: 10116)
Breed/subspecies: AxC; RS=RS:0000369. |
Hierarchy | Parent: CVCL_0284 (H4-II-E) |
Sex of cell | Male |
Category | Cancer cell line |
Publications | PubMed=8812260; DOI=10.1006/faat.1996.0152 PubMed=8812265; DOI=10.1006/faat.1996.0056 Patent=US5854010 PubMed=18969542; DOI=10.1016/j.talanta.2004.05.032 PubMed=21394221; DOI=10.1007/s11426-010-0142-8; PMCID=PMC3049243 PubMed=26366531; DOI=10.1021/acs.est.5b02906; PMCID=PMC4772899 |
Cross-references | |
Encyclopedic resources | Wikidata; Q54872158 |
Entry history | |
Entry creation | 13-Jul-2016 |
Last entry update | 10-Sep-2024 |
Version number | 8 |