Cellosaurus H1L6.1c3 (CVCL_DC23)
Cell line name | H1L6.1c3 |
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Accession | CVCL_DC23 |
Resource Identification Initiative | To cite this cell line use: H1L6.1c3 (RRID:CVCL_DC23) |
Comments | Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists. Biotechnology: Used in US Environmental Protection Agency (EPA) hazardous waste test method 4435 (SW-846). Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
Disease | Hepatocellular carcinoma of the mouse (NCIt: C38756) |
Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57L/J. |
Hierarchy | Parent: CVCL_0328 (Hepa-1c1c7) |
Sex of cell | Female |
Category | Cancer cell line |
Web pages | https://www.epa.gov/hw-sw846/sw-846-test-method-4435-screening-dioxin-chemical-activity-soils-and-sediments-using-calux http://www.dioxins.com/calux2.html |
Publications | PubMed=18969542; DOI=10.1016/j.talanta.2004.05.032 PubMed=21872055; DOI=10.1016/j.talanta.2011.07.042 PubMed=26366531; DOI=10.1021/acs.est.5b02906; PMCID=PMC4772899 |
Cross-references | |
Encyclopedic resources | Wikidata; Q54871989 |
Entry history | |
Entry creation | 13-Jul-2016 |
Last entry update | 19-Dec-2024 |
Version number | 11 |