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Cellosaurus G16L7.5c1 (CVCL_DC18)

[Text version]
Cell line name G16L7.5c1
Accession CVCL_DC18
Resource Identification Initiative To cite this cell line use: G16L7.5c1 (RRID:CVCL_DC18)
Comments Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Transformant: ChEBI; CHEBI_50102; N-methyl-N-nitrosourea (NMU).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Disease Guinea pig colon adenocarcinoma (NCIt: C134563)
Species of origin Cavia porcellus (Guinea pig) (NCBI Taxonomy: 10141)
Hierarchy Parent: CVCL_3463 (GPC-16)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=26366531; DOI=10.1021/acs.est.5b02906; PMCID=PMC4772899
Brennan J.C., He G.-C., Tsutsumi T., Zhao J., Wirth E., Fulton M.H., Denison M.S.
Development of species-specific Ah receptor-responsive third generation CALUX cell lines with enhanced responsiveness and improved detection limits.
Environ. Sci. Technol. 49:11903-11912(2015)

Cross-references
Encyclopedic resources Wikidata; Q54835370
Entry history
Entry creation13-Jul-2016
Last entry update19-Dec-2024
Version number11