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Cellosaurus NZM007.2 (CVCL_D844)

[Text version]
Cell line name NZM007.2
Synonyms NZM07.2; NZM7.2
Accession CVCL_D844
Resource Identification Initiative To cite this cell line use: NZM007.2 (RRID:CVCL_D844)
Comments Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9612; PTK2B; Simple; p.Arg429Cys (c.1285C>T); dbSNP=rs201274282; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser241Pro (c.721T>C); ClinVar=VCV000376664; Zygosity=Unspecified (PubMed=11216673).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D843 (NZM007)
Sex of cell Male
Age at sampling 36Y
Category Cancer cell line
Publications

PubMed=11216673; DOI=10.3727/096504001108747620
Parmar J., Marshall E.S., Charters G.A., Holdaway K.M., Shelling A.N., Baguley B.C.
Radiation-induced cell cycle delays and p53 status of early passage melanoma cell lines.
Oncol. Res. 12:149-155(2000)

PubMed=20041153; DOI=10.1371/journal.pone.0008461
Jeffs A.R., Glover A.C., Slobbe L.J., Wang L., He S.-J., Hazlett J.A., Awasthi A., Woolley A.G., Marshall E.S., Joseph W.R., Print C.G., Baguley B.C., Eccles M.R.
A gene expression signature of invasive potential in metastatic melanoma cells.
PLoS ONE 4:E8461-E8461(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D844
Encyclopedic resources Wikidata; Q54931609
Polymorphism and mutation databases IARC_TP53; 14965
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number15