Cellosaurus logo
expasy logo

Cellosaurus NZM006 (CVCL_D842)

[Text version]
Cell line name NZM006
Synonyms NZM06; NZM6
Accession CVCL_D842
Resource Identification Initiative To cite this cell line use: NZM006 (RRID:CVCL_D842)
Comments Doubling time: 34 hours (PubMed=7718330); 50 hours (CBA=CBA-1386).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Small intestine; UBERON=UBERON_0002108.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): CBA=CBA-1386; PubMed=32567790

Markers:
AmelogeninX
CSF1PO10,11
D2S133820
D3S135815
D5S81811,12
D7S82011
D8S117912,13
D13S31710,14
D16S53911
D18S5113,15
D19S43314
D21S1128,31
FGA20.1,23 (PubMed=32567790)
20.2,23 (CBA=CBA-1386)
TH017
TPOX12
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=7999427; DOI=10.1016/0959-8049(94)90188-0
Marshall E.S., Matthews J.H.L., Shaw J.H.F., Nixon J., Tumewu P., Finlay G.J., Holdaway K.M., Baguley B.C.
Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays.
Eur. J. Cancer 30A:1370-1376(1994)

PubMed=7718330; DOI=10.1016/0959-8049(94)00472-H
Baguley B.C., Marshall E.S., Whittaker J.R., Dotchin M.C., Nixon J., McCrystal M.R., Finlay G.J., Matthews J.H.L., Holdaway K.M., van Zijl P.L.
Resistance mechanisms determining the in vitro sensitivity to paclitaxel of tumour cells cultured from patients with ovarian cancer.
Eur. J. Cancer 31A:230-237(1995)

PubMed=11216673; DOI=10.3727/096504001108747620
Parmar J., Marshall E.S., Charters G.A., Holdaway K.M., Shelling A.N., Baguley B.C.
Radiation-induced cell cycle delays and p53 status of early passage melanoma cell lines.
Oncol. Res. 12:149-155(2000)

PubMed=20041153; DOI=10.1371/journal.pone.0008461; PMCID=PMC2794539
Jeffs A.R., Glover A.C., Slobbe L.J., Wang L., He S.-J., Hazlett J.A., Awasthi A., Woolley A.G., Marshall E.S., Joseph W.R., Print C.G., Baguley B.C., Eccles M.R.
A gene expression signature of invasive potential in metastatic melanoma cells.
PLoS ONE 4:E8461-E8461(2009)

CLPUB00227
Daukste L.
Mathematical modelling of cancer cell population dynamics.
Thesis PhD (2012); University of Canterbury; Christchurch; New Zealand

PubMed=22475322; DOI=10.1186/1471-2407-12-141; PMCID=PMC3352269
Kim J.E., Stones C.J., Joseph W.R., Leung E.Y., Finlay G.J., Shelling A.N., Phillips W.A., Shepherd P.R., Baguley B.C.
Comparison of growth factor signalling pathway utilisation in cultured normal melanocytes and melanoma cell lines.
BMC Cancer 12:141.1-141.10(2012)

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C.
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=24455489; DOI=10.3389/fonc.2013.00333; PMCID=PMC3888952
D'mello S.A.N., Flanagan J.U., Green T.N., Leung E.Y., Askarian-Amiri M.E., Joseph W.R., McCrystal M.R., Isaacs R.J., Shaw J.H.F., Furneaux C.E., During M.J., Finlay G.J., Baguley B.C., Kalev-Zylinska M.L.
Evidence that GRIN2A mutations in melanoma correlate with decreased survival.
Front. Oncol. 3:333.1-333.9(2014)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line collections (Providers) CBA; CBA-1386
Cell line databases/resources cancercelllines; CVCL_D842
Biological sample resources BioSample; SAMN07624450
BioSample; SAMN14558317
Encyclopedic resources Wikidata; Q54931595
Polymorphism and mutation databases Cosmic; 1660289
Cosmic; 2007647
Cosmic; 2406333
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number20