ID   NZM045
AC   CVCL_D835
SY   NZM45
DR   BioSample; SAMN14558341
DR   cancercelllines; CVCL_D835
DR   Cosmic; 2007677
DR   Wikidata; Q54931579
RX   PubMed=20041153;
RX   PubMed=23658559;
RX   PubMed=32567790;
CC   Sequence variation: Mutation; HGNC; HGNC:4379; GNA11; Simple; p.Arg183Cys (c.547C>T); ClinVar=VCV000548668; Zygosity=Heterozygous (PubMed=32567790).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
ST   Source(s): PubMed=32567790
ST   Amelogenin: X
ST   CSF1PO: 11,13
ST   D13S317: 8,14
ST   D16S539: 11,12
ST   D18S51: 15,17
ST   D19S433: 14,15
ST   D21S11: 30,31.2
ST   D2S1338: 17,24
ST   D3S1358: 16,18
ST   D5S818: 11
ST   D7S820: 8,11
ST   D8S1179: 13,15
ST   FGA: 23
ST   TH01: 9.3
ST   TPOX: 8,11
ST   vWA: 16,17
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 15
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RX   PubMed=20041153; DOI=10.1371/journal.pone.0008461; PMCID=PMC2794539;
RA   Jeffs A.R., Glover A.C., Slobbe L.J., Wang L., He S.-J., Hazlett J.A.,
RA   Awasthi A., Woolley A.G., Marshall E.S., Joseph W.R., Print C.G.,
RA   Baguley B.C., Eccles M.R.;
RT   "A gene expression signature of invasive potential in metastatic
RT   melanoma cells.";
RL   PLoS ONE 4:E8461-E8461(2009).
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RX   PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113;
RA   Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S.,
RA   Finlay G.J., Shelling A.N., Baguley B.C.;
RT   "Comparison of responses of human melanoma cell lines to MEK and BRAF
RT   inhibitors.";
RL   Front. Genet. 4:66.1-66.6(2013).
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RX   PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249;
RA   Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J.,
RA   Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S.,
RA   Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.;
RT   "Genomic and signalling pathway characterization of the NZM panel of
RT   melanoma cell lines: a valuable model for studying the impact of
RT   genetic diversity in melanoma.";
RL   Pigment Cell Melanoma Res. 34:136-143(2021).
//