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Cellosaurus NZM034 (CVCL_D830)

[Text version]
Cell line name NZM034
Synonyms NZM34
Accession CVCL_D830
Resource Identification Initiative To cite this cell line use: NZM034 (RRID:CVCL_D830)
Comments Doubling time: 40.8 hours (CelloPub=CLPUB00227).
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX,Y
CSF1PO11
D2S133817,25
D3S135815
D5S81811,12
D7S82010,12
D8S117912,15
D13S3178,12
D16S53912,13
D18S5112,17
D19S43313,16.2
D21S1131
FGA20,25
TH016
TPOX8,9
vWA16,17

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Publications

CLPUB00227
Daukste L.
Mathematical modelling of cancer cell population dynamics.
Thesis PhD (2012); University of Canterbury; Christchurch; New Zealand

PubMed=22475322; DOI=10.1186/1471-2407-12-141; PMCID=PMC3352269
Kim J.E., Stones C.J., Joseph W.R., Leung E.Y., Finlay G.J., Shelling A.N., Phillips W.A., Shepherd P.R., Baguley B.C.
Comparison of growth factor signalling pathway utilisation in cultured normal melanocytes and melanoma cell lines.
BMC Cancer 12:141.1-141.10(2012)

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C.
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=24455489; DOI=10.3389/fonc.2013.00333; PMCID=PMC3888952
D'mello S.A.N., Flanagan J.U., Green T.N., Leung E.Y., Askarian-Amiri M.E., Joseph W.R., McCrystal M.R., Isaacs R.J., Shaw J.H.F., Furneaux C.E., During M.J., Finlay G.J., Baguley B.C., Kalev-Zylinska M.L.
Evidence that GRIN2A mutations in melanoma correlate with decreased survival.
Front. Oncol. 3:333.1-333.9(2014)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D830
Encyclopedic resources Wikidata; Q54931566
Polymorphism and mutation databases Cosmic; 1660290
Cosmic; 2007667
Cosmic; 2406335
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number17