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Cellosaurus NZM030 (CVCL_D829)

[Text version]
Cell line name NZM030
Synonyms NZM30
Accession CVCL_D829
Resource Identification Initiative To cite this cell line use: NZM030 (RRID:CVCL_D829)
Comments Doubling time: 29.6 hours (CelloPub=CLPUB00227); 80-90 hours (CBA=CBA-1399).
Omics: Deep exome analysis.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 41Y
Category Cancer cell line
STR profile Source(s): CBA=CBA-1399; PubMed=32567790

Markers:
AmelogeninX
CSF1PO10
D2S133817
D3S135814
D5S81811
D7S82011
D8S117913,14
D13S31711,12
D16S53910,12
D18S5112,13
D19S43314,17.2
D21S1124.2,31
FGA21,22
Penta D9
Penta E7,12
TH019
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

CLPUB00227
Daukste L.
Mathematical modelling of cancer cell population dynamics.
Thesis PhD (2012); University of Canterbury; Christchurch; New Zealand

PubMed=22475322; DOI=10.1186/1471-2407-12-141; PMCID=PMC3352269
Kim J.E., Stones C.J., Joseph W.R., Leung E.Y., Finlay G.J., Shelling A.N., Phillips W.A., Shepherd P.R., Baguley B.C.
Comparison of growth factor signalling pathway utilisation in cultured normal melanocytes and melanoma cell lines.
BMC Cancer 12:141.1-141.10(2012)

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C.
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=24455489; DOI=10.3389/fonc.2013.00333; PMCID=PMC3888952
D'mello S.A.N., Flanagan J.U., Green T.N., Leung E.Y., Askarian-Amiri M.E., Joseph W.R., McCrystal M.R., Isaacs R.J., Shaw J.H.F., Furneaux C.E., During M.J., Finlay G.J., Baguley B.C., Kalev-Zylinska M.L.
Evidence that GRIN2A mutations in melanoma correlate with decreased survival.
Front. Oncol. 3:333.1-333.9(2014)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line collections (Providers) CBA; CBA-1399
Cell line databases/resources cancercelllines; CVCL_D829
Biological sample resources BioSample; SAMN07624444
BioSample; SAMN14558331
Encyclopedic resources Wikidata; Q54931562
Polymorphism and mutation databases Cosmic; 1660292
Cosmic; 2007664
Cosmic; 2406334
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number20