Cellosaurus logo
expasy logo

Cellosaurus NZM022 (CVCL_D825)

[Text version]
Cell line name NZM022
Synonyms NZM22
Accession CVCL_D825
Resource Identification Initiative To cite this cell line use: NZM022 (RRID:CVCL_D825)
Comments Doubling time: 81.4 hours (CelloPub=CLPUB00227).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly466Ala (c.1397G>C); ClinVar=VCV000376295; Zygosity=Heterozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.Arg1362Ter (c.4084C>T); ClinVar=VCV000000344; Zygosity=Unspecified (PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX
CSF1PO12
D2S133817,19
D3S135814,16
D5S81811
D7S8209,11
D8S117913,14
D13S31711,13
D16S53912
D18S5112,13
D19S43313,14
D21S1127,29
FGA20,21
TH019
TPOX8,10
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=20041153; DOI=10.1371/journal.pone.0008461; PMCID=PMC2794539
Jeffs A.R., Glover A.C., Slobbe L.J., Wang L., He S.-J., Hazlett J.A., Awasthi A., Woolley A.G., Marshall E.S., Joseph W.R., Print C.G., Baguley B.C., Eccles M.R.
A gene expression signature of invasive potential in metastatic melanoma cells.
PLoS ONE 4:E8461-E8461(2009)

CLPUB00227
Daukste L.
Mathematical modelling of cancer cell population dynamics.
Thesis PhD (2012); University of Canterbury; Christchurch; New Zealand

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C.
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=23755070; DOI=10.3389/fgene.2013.00097; PMCID=PMC3668138
Kim J.E., Leung E.Y., Baguley B.C., Finlay G.J.
Heterogeneity of expression of epithelial-mesenchymal transition markers in melanocytes and melanoma cell lines.
Front. Genet. 4:97.1-97.8(2013)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D825
Biological sample resources BioSample; SAMN14558327
Encyclopedic resources Wikidata; Q54931548
Polymorphism and mutation databases Cosmic; 2007659
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number14