Cellosaurus logo
expasy logo

Cellosaurus NZM002 (CVCL_D823)

[Text version]
Cell line name NZM002
Synonyms NZM02; NZM2
Accession CVCL_D823
Resource Identification Initiative To cite this cell line use: NZM002 (RRID:CVCL_D823)
Comments Doubling time: 43.2 hours (CelloPub=CLPUB00227); 70 hours (CBA=CBA-1378).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Iliac lymph node; UBERON=UBERON_0015878.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D815 ! NZM001
Sex of cell Male
Age at sampling 47Y
Category Cancer cell line
STR profile Source(s): CBA=CBA-1378; PubMed=32567790

Markers:
AmelogeninX
CSF1PO10
D2S133817,23
D3S135817
D5S81811
D7S82011,12
D8S117913,15
D13S31710,11
D16S5399,12
D18S5119
D19S43313,15
D21S1127,32.2
FGA21,23
TH016,8
TPOX10,12
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=7999427; DOI=10.1016/0959-8049(94)90188-0
Marshall E.S., Matthews J.H.L., Shaw J.H.F., Nixon J., Tumewu P., Finlay G.J., Holdaway K.M., Baguley B.C.
Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays.
Eur. J. Cancer 30A:1370-1376(1994)

PubMed=11216673; DOI=10.3727/096504001108747620
Parmar J., Marshall E.S., Charters G.A., Holdaway K.M., Shelling A.N., Baguley B.C.
Radiation-induced cell cycle delays and p53 status of early passage melanoma cell lines.
Oncol. Res. 12:149-155(2000)

PubMed=20041153; DOI=10.1371/journal.pone.0008461; PMCID=PMC2794539
Jeffs A.R., Glover A.C., Slobbe L.J., Wang L., He S.-J., Hazlett J.A., Awasthi A., Woolley A.G., Marshall E.S., Joseph W.R., Print C.G., Baguley B.C., Eccles M.R.
A gene expression signature of invasive potential in metastatic melanoma cells.
PLoS ONE 4:E8461-E8461(2009)

CLPUB00227
Daukste L.
Mathematical modelling of cancer cell population dynamics.
Thesis PhD (2012); University of Canterbury; Christchurch; New Zealand

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C.
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line collections (Providers) CBA; CBA-1378
Biological sample resources BioSample; SAMN07624442
BioSample; SAMN14558313
Encyclopedic resources Wikidata; Q54931542
Polymorphism and mutation databases Cosmic; 2007643
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number19