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Cellosaurus NZM014 (CVCL_D820)

[Text version]
Cell line name NZM014
Synonyms NZM14
Accession CVCL_D820
Resource Identification Initiative To cite this cell line use: NZM014 (RRID:CVCL_D820)
Comments Omics: Deep exome analysis.
Derived from site: Metastatic; Thigh, skeletal muscle; UBERON=UBERON_0004252.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Lys (c.1798_1799delGTinsAA); ClinVar=VCV000375941; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817
D3S135815
D5S81812
D7S8207,8
D8S117911,13
D13S31711
D16S53911,13
D18S5113,16
D19S43315
D21S1128
FGA21,22
TH017,9.3
TPOX8,10
vWA14,19

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Publications

PubMed=11216673; DOI=10.3727/096504001108747620
Parmar J., Marshall E.S., Charters G.A., Holdaway K.M., Shelling A.N., Baguley B.C.
Radiation-induced cell cycle delays and p53 status of early passage melanoma cell lines.
Oncol. Res. 12:149-155(2000)

PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113
Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C.
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D820
Biological sample resources BioSample; SAMN14558323
Encyclopedic resources Wikidata; Q54931530
Polymorphism and mutation databases Cosmic; 2007653
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number19