ID   NZM013
AC   CVCL_D819
SY   NZM13
DR   BioSample; SAMN14558322
DR   cancercelllines; CVCL_D819
DR   Cosmic; 2007652
DR   Wikidata; Q54931529
RX   CelloPub=CLPUB00227;
RX   PubMed=11216673;
RX   PubMed=23658559;
RX   PubMed=23755070;
RX   PubMed=32567790;
CC   Doubling time: 76.8 hours (CelloPub=CLPUB00227).
CC   HLA typing: A*02:01,03:01; B*15:01,35:01; C*03:03,04:01 (PubMed=32567790).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Leu (c.3140A>T); ClinVar=VCV000013653; Zygosity=Heterozygous (PubMed=32567790).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: Metastatic; Neck, hypodermis; UBERON=UBERON_0000974+UBERON_0002072.
ST   Source(s): PubMed=32567790
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11,12
ST   D16S539: 13
ST   D18S51: 17
ST   D19S433: 13,14
ST   D21S11: 30,32.2
ST   D2S1338: 19,24
ST   D3S1358: 15,16
ST   D5S818: 11,12
ST   D7S820: 8
ST   D8S1179: 11,15
ST   FGA: 19,22
ST   TH01: 7,9.3
ST   TPOX: 11
ST   vWA: 15
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   81Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 16
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RX   CelloPub=CLPUB00227;
RA   Daukste L.;
RT   "Mathematical modelling of cancer cell population dynamics.";
RL   Thesis PhD (2012); University of Canterbury; Christchurch; New Zealand.
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RX   PubMed=11216673; DOI=10.3727/096504001108747620;
RA   Parmar J., Marshall E.S., Charters G.A., Holdaway K.M., Shelling A.N.,
RA   Baguley B.C.;
RT   "Radiation-induced cell cycle delays and p53 status of early passage
RT   melanoma cell lines.";
RL   Oncol. Res. 12:149-155(2000).
//
RX   PubMed=23658559; DOI=10.3389/fgene.2013.00066; PMCID=PMC3647113;
RA   Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S.,
RA   Finlay G.J., Shelling A.N., Baguley B.C.;
RT   "Comparison of responses of human melanoma cell lines to MEK and BRAF
RT   inhibitors.";
RL   Front. Genet. 4:66.1-66.6(2013).
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RX   PubMed=23755070; DOI=10.3389/fgene.2013.00097; PMCID=PMC3668138;
RA   Kim J.E., Leung E.Y., Baguley B.C., Finlay G.J.;
RT   "Heterogeneity of expression of epithelial-mesenchymal transition
RT   markers in melanocytes and melanoma cell lines.";
RL   Front. Genet. 4:97.1-97.8(2013).
//
RX   PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249;
RA   Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J.,
RA   Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S.,
RA   Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.;
RT   "Genomic and signalling pathway characterization of the NZM panel of
RT   melanoma cell lines: a valuable model for studying the impact of
RT   genetic diversity in melanoma.";
RL   Pigment Cell Melanoma Res. 34:136-143(2021).
//