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Cellosaurus Ubigene A-431 TLR3 KO (CVCL_D7JA)

[Text version]
Cell line name Ubigene A-431 TLR3 KO
Synonyms TLR3 Knockout cell line (A-431)
Accession CVCL_D7JA
Resource Identification Initiative To cite this cell line use: Ubigene A-431 TLR3 KO (RRID:CVCL_D7JA)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11849; TLR3.
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Sequence variations
  • Gene fusion; HGNC; HGNC:3236; EGFR + HGNC; HGNC:9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0037 (A-431)
Sex of cell Female
Age at sampling 85Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-H072
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2