Cellosaurus logo
expasy logo

Cellosaurus Ubigene 5637 SPOP KO (CVCL_D7IV)

[Text version]
Cell line name Ubigene 5637 SPOP KO
Synonyms SPOP Knockout cell line (5637)
Accession CVCL_D7IV
Resource Identification Initiative To cite this cell line use: Ubigene 5637 SPOP KO (RRID:CVCL_D7IV)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; 11254; SPOP.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; 6871; MAPK1; Simple; p.Arg79Lys (c.236G>A); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Tyr325Ter (c.975T>A); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg280Thr (c.839G>C); ClinVar=VCV000012368; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0126 (5637)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-H520
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1