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Cellosaurus HeLa M TBK1-KO + TBK1-E696K-GFP (CVCL_D7EV)

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Cell line name HeLa M TBK1-KO + TBK1-E696K-GFP
Accession CVCL_D7EV
Resource Identification Initiative To cite this cell line use: HeLa M TBK1-KO + TBK1-E696K-GFP (RRID:CVCL_D7EV)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11584; TBK1.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11584; TBK1 (Note=With p.Glu696Lys).
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D7ES (HeLa M TBK1-KO)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=38168426; DOI=10.1101/2023.12.16.571979; PMCID=PMC10760094
Talaia G., Bentley-DeSousa A., Ferguson S.M.
Lysosomal TBK1 responds to amino acid availability to relieve Rab7-dependent mTORC1 inhibition.
bioRxiv 2023:12.16.571979-12.16.571979(2023)

Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1