ID   HEK293T_HTT null
AC   CVCL_D7EP
RX   PubMed=33432339;
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 4851; HTT.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0063 ! HEK293T
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 10-09-24; Last updated: 10-09-24; Version: 1
//
RX   PubMed=33432339; DOI=10.1093/hmg/ddaa283; PMCID=PMC8248964;
RA   Jung R., Lee Y., Barker D., Correia K., Shin B., Loupe J.,
RA   Collins R.L., Lucente D., Ruliera J., Gillis T., Mysore J.S.,
RA   Rodan L., Picker J., Lee J.-M., Howland D.S., Lee R., Kwak S.,
RA   MacDonald M.E., Gusella J.F., Seong I.S.;
RT   "Mutations causing Lopes-Maciel-Rodan syndrome are huntingtin
RT   hypomorphs.";
RL   Hum. Mol. Genet. 30:135-148(2021).
//