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Cellosaurus M257 (CVCL_D757)

[Text version]
Cell line name M257
Accession CVCL_D757
Resource Identification Initiative To cite this cell line use: M257 (RRID:CVCL_D757)
Comments Part of: MD Anderson Cell Lines Project.
Doubling time: 31.4 hours (PubMed=20406486).
Omics: Protein expression by reverse-phase protein arrays.
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=20406486; DOI=10.1186/1479-5876-8-39
Sondergaard J.N., Nazarian R., Wang Q., Guo D.-L., Hsueh T., Mok S., Sazegar H., MacConaill L.E., Barretina J.G., Kehoe S.M., Attar N., von Euw E.M., Zuckerman J.E., Chmielowski B., Comin-Anduix B., Koya R.C., Mischel P.S., Lo R.S., Ribas A.
Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.
J. Transl. Med. 8:39.1-39.11(2010)

PubMed=20689758; DOI=10.1593/neo.10414
Tap W.D., Gong K.-W., Dering J., Tseng Y., Ginther C., Pauletti G., Glaspy J.A., Essner R., Bollag G., Hirth P., Zhang C., Slamon D.J.
Pharmacodynamic characterization of the efficacy signals due to selective BRAF inhibition with PLX4032 in malignant melanoma.
Neoplasia 12:637-649(2010)

PubMed=22515704; DOI=10.1186/1476-4598-11-22
von Euw E.M., Atefi M., Attar N., Chu C., Zachariah S., Burgess B.L., Mok S., Ng C., Wong D.J.L., Chmielowski B., Lichter D.I., Koya R.C., McCannel T.A., Izmailova E., Ribas A.
Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines.
Mol. Cancer 11:22.1-22.9(2012)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Encyclopedic resources Wikidata; Q54903569
Polymorphism and mutation databases Cosmic; 1425342
Cosmic; 1459668
Cosmic; 1665178
Cosmic; 1949555
Entry history
Entry creation22-Oct-2012
Last entry update21-Mar-2023
Version number10