• Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Unspecified (PubMed=29492214).
  
• Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Homozygous (PubMed=25645078; PubMed=29492214).
  

PubMed=2064308
Verschraegen C.F., Giovanella B.C., Mendoza J.T., Kozielski A.J., Stehlin J.S. Jr.
Specific organ metastases of human melanoma cells injected into the arterial circulation of nude mice.
Anticancer Res. 11:529-535(1991)

PubMed=21424129; DOI=10.3892/or.2011.1220
Manca A., Sini M.C., Izzo F., Ascierto P.A., Tatangelo F., Botti G., Gentilcore G., Capone M., Mozzillo N., Rozzo C., Cossu A., Tanda F., Palmieri G.
Induction of arginosuccinate synthetase (ASS) expression affects the antiproliferative activity of arginine deiminase (ADI) in melanoma cells.
Oncol. Rep. 25:1495-1502(2011)

PubMed=21863025; DOI=10.1038/bjc.2011.324; PMCID=PMC3185940
De Luca A., Lamura L., Strizzi L., Roma C., D'Antonio A., Margaryan N.V., Pirozzi G., Hsu M.-Y., Botti G., Mari E., Hendrix M.J.C., Salomon D.S., Normanno N.
Expression and functional role of CRIPTO-1 in cutaneous melanoma.
Br. J. Cancer 105:1030-1038(2011)

PubMed=25645078; DOI=10.1186/s12943-015-0293-5; PMCID=PMC4320814
Atefi M., Titz B., Avramis E., Ng C., Wong D.J.L., Lassen A., Cerniglia M., Escuin-Ordinas H., Foulad D., Comin-Anduix B., Graeber T.G., Ribas A.
Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma.
Mol. Cancer 14:27.1-27.12(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29492214; DOI=10.18632/oncotarget.23989; PMCID=PMC5823576
Sini M.C., Doneddu V., Paliogiannis P., Casula M., Colombino M., Manca A., Botti G., Ascierto P.A., Lissia A., Cossu A., Palmieri G.
Genetic alterations in main candidate genes during melanoma progression.
Oncotarget 9:8531-8541(2018)