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Cellosaurus HCC38rGEM20 (CVCL_D6VN)

[Text version]
Cell line name HCC38rGEM20
Synonyms HCC38 rGemcitabine20
Accession CVCL_D6VN
Resource Identification Initiative To cite this cell line use: HCC38rGEM20 (RRID:CVCL_D6VN)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273Leu (c.818G>T); ClinVar=VCV000376655; Zygosity=Homozygous (from parent cell line).
Disease Breast ductal carcinoma (NCIt: C4017)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1267 (HCC38)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
Publications

DOI=10.1101/2024.01.20.576412
Grimsley H.E., Antczak M., McLaughlin K.-M., Nist A., Mernberger M., Stiewe T., Speidel D., Cox K., Cinatl J. Jr., Wass M.N., Garrett M.D., Michaelis M.
Resistance patterns in drug-adapted cancer cell lines reflect complex evolution in clinical tumors.
bioRxiv 2024:01.20.576412-01.20.576412(2024)

Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1