Cellosaurus cell line HCC1806r5-F1500 (CVCL

Cellosaurus HCC1806r5-F1500 (CVCL_D6VJ)

Entry history
Cell line name	HCC1806r5-F1500
Synonyms	HCC1806 r5-Fluorouracil1500
Accession	CVCL_D6VJ
Resource Identification Initiative	To cite this cell line use: HCC1806r5-F1500 (RRID:CVCL_D6VJ)
Comments	Group: Triple negative breast cancer (TNBC) cell line. Part of: Resistant Cancer Cell Line (RCCL) collection. Population: African American. Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU). Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr256Lysfs*90 (c.766_767insAA); Zygosity=Heterozygous (from parent cell line).
Disease	Breast acantholytic squamous cell carcinoma (NCIt: C40359)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1258 (HCC1806)
Sex of cell	Female
Age at sampling	60Y
Category	Cancer cell line
Publications	PubMed=40300663; DOI=10.1016/j.canlet.2025.217754 Helen E. Grimsley, Magdalena Antczak, Ian G. Reddin, Nicole Weiler, Katie-May McLaughlin, Florian Rothweiler, Johannes Haas, Andrea Nist, Marco Mernberger, Thorsten Stiewe, Tim R. Fenton ...Show all 19 authors... , Daniel Speidel, Catherine Harper-Wynne, Karina Cox, Dirk Heckl, Jindrich Cinatl Jr., Mark N. Wass, Michelle D. Garrett, Martin Michaelis; Show fewer authors Using a novel panel of drug-resistant triple-negative breast cancer cell lines to identify candidate therapeutic targets and biomarkers. Cancer Lett. 624:217754.1-217754.14(2025)
Entry creation	10-Sep-2024
Last entry update	14-Aug-2025
Version number	4