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Cellosaurus MCRIi010-A-1 (CVCL_D6MK)

[Text version]
Cell line name MCRIi010-A-1
Synonyms PB010.5-ACTA1tdTom; ACTA1tdTom
Accession CVCL_D6MK
Resource Identification Initiative To cite this cell line use: MCRIi010-A-1 (RRID:CVCL_D6MK)
Comments From: Murdoch Children's Research Institute; Melbourne; Australia.
Population: Caucasian.
Characteristics: Using CRISPR/Cas9 a P2A-tdTomato construct was inserted at the C-terminus of both alleles of ACTA1 (PubMed=38277710).
Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UK91 (MCRIi010-A)
Sex of cell Male
Age at sampling 22Y
Category Induced pluripotent stem cell
Publications

PubMed=38277710; DOI=10.1016/j.scr.2024.103313
Houweling P.J., Crossman V., Tiong C.F., Coles C.A., Taylor R.L., Clayton J.S., Graham A., Vlahos K., Howden S.E., North K.N.
Generation of a human ACTA1-tdTomato reporter iPSC line using CRISPR/Cas9 editing.
Stem Cell Res. 75:103313-103313(2024)

Cross-references
Cell line databases/resources hPSCreg; MCRIi010-A-1
Encyclopedic resources Wikidata; Q127382750
Entry history
Entry creation02-May-2024
Last entry update10-Sep-2024
Version number2